In spite of his many shortcomings, he is a nice guy.
盡管他有許多缺點(diǎn),但他還是個(gè)好人。
in spite of表示盡管,不管;整個(gè)in spite of其實(shí)可用一個(gè)despite來(lái)替換,意思一樣。
despite his many shortcomings,he is a nice guy.
He went to work in spite of his illness.(當(dāng)中的in spite of也可改為despite)
盡管生病,他還是去工作。