新型艾滋病疫苗在猴子身上證明有效

American researchers have recently developed a new type of AIDS vaccine. Monkey experiments show that vaccination with this vaccine can protect them from HIV-like infections. This brings new hope for the prevention and treatment of AIDS.

美國(guó)研究人員最近開發(fā)出一種新型艾滋病疫苗，猴子實(shí)驗(yàn)顯示，接種這種疫苗能保護(hù)它們免受與人艾滋病病毒相似病毒的感染。這為防治艾滋病帶來(lái)了新希望。

Researchers from Scripps Institution and other institutions in the United States recently reported the results in the American academic journal Immunity. They developed the vaccine against weaknesses in the protein coat of HIV, which triggers the immune system to produce an antibody that can attack virus-related weaknesses and thus play a protective role.

美國(guó)斯克里普斯研究所等機(jī)構(gòu)研究人員近日在美國(guó)學(xué)術(shù)刊物《免疫》上報(bào)告了相關(guān)成果。他們針對(duì)艾滋病病毒蛋白質(zhì)外殼上的弱點(diǎn)開發(fā)了這種疫苗，疫苗會(huì)引發(fā)免疫系統(tǒng)產(chǎn)生一種抗體，該抗體能夠攻擊病毒相關(guān)弱點(diǎn)，從而起到保護(hù)作用。

Researchers injected different doses of new vaccines into some rhesus monkeys, some of which produced high levels of antibodies and others produced low levels of antibodies. When confronted with monkey immunodeficiency virus (SIV), which is very similar to human HIV, monkeys that produce high levels of antibodies in vivo can be protected from infection. Researchers say this will help determine the appropriate dosage for future use of the vaccine.

研究人員給一些恒河猴注射了不同劑量的新疫苗，其中一些猴子體內(nèi)產(chǎn)生了高水平抗體，另一些猴子體內(nèi)產(chǎn)生了低水平抗體。當(dāng)面臨與人艾滋病病毒非常相似的猴免疫缺陷病毒時(shí)，體內(nèi)產(chǎn)生高水平抗體的猴子能夠免受感染。研究人員說(shuō)，這有助于確定今后使用這種疫苗的合適劑量。

It is reported that some of the previous ideas of AIDS vaccine research and development rely on the immune system T cells to play a role, and this new vaccine relies on the aforementioned antibodies to play a role, its mechanism is different, adding new ideas for the prevention and treatment of AIDS.

據(jù)介紹，此前一些艾滋病疫苗的研發(fā)思路是依靠免疫系統(tǒng)的T細(xì)胞等發(fā)揮作用，而這種新型疫苗依靠前述抗體起作用，其作用機(jī)理不同，為防治艾滋病增加了新思路。

Researchers next plan to carry out human clinical trials to try to put the new vaccine into use as soon as possible.

研究人員接下來(lái)計(jì)劃開展人類臨床試驗(yàn)，爭(zhēng)取早日將這種新型疫苗投入應(yīng)用。